Abstract
A mechanistic investigation of the Pd-catalyzed conversion of aryl triflates to fluorides is presented. Studies reveal that C-F reductive elimination from a LPd(II)(aryl)F complex (L = t-BuBrettPhos or RockPhos) does not occur when the aryl group is electron rich. Evidence is presented that a modified phosphine, generated in situ, serves as the actual supporting ligand during catalysis with such substrates. A preliminary study of the reactivity of a LPd(II)(aryl)F complex based on this modified ligand is reported.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
-
Catalysis
-
Hydrocarbons, Fluorinated / chemical synthesis*
-
Hydrocarbons, Fluorinated / chemistry
-
Mesylates / chemistry*
-
Models, Molecular
-
Molecular Structure
-
Organometallic Compounds / chemical synthesis
-
Organometallic Compounds / chemistry*
-
Palladium / chemistry*
-
Stereoisomerism
Substances
-
Hydrocarbons, Fluorinated
-
Mesylates
-
Organometallic Compounds
-
Palladium
-
trifluoromethanesulfonic acid