Extensively drug-resistant tuberculosis case in the Thames Valley, UK and public health interventions

Muhammad Abid; Noel McCarthy; Luisa Saldaña; Tracey Langham; Anne McGown; Christopher Conlon; Pablo de Vena Franks

doi:10.1016/j.jiph.2011.06.003

Extensively drug-resistant tuberculosis case in the Thames Valley, UK and public health interventions

J Infect Public Health. 2011 Sep;4(4):207-10. doi: 10.1016/j.jiph.2011.06.003. Epub 2011 Sep 13.

Authors

Muhammad Abid¹, Noel McCarthy, Luisa Saldaña, Tracey Langham, Anne McGown, Christopher Conlon, Pablo de Vena Franks

Affiliation

¹ Thames Valley Health Protection Unit, Chilton, Oxfordshire, UK. [email protected]

PMID: 22000849
DOI: 10.1016/j.jiph.2011.06.003

Abstract

This study describes the first case of extensively drug-resistant tuberculosis (XDR-TB) in the Thames Valley and South East Region and discuss the public health implications, highlighting the need to integrate current epidemiological knowledge with clinical expertise in order to diagnose drug-resistant tuberculosis (TB) early. The management of the XDR-TB patients is challenging with few treatment options, expensive therapy, side effects of drugs and a longer course of the treatment.

Publication types

Case Reports

MeSH terms

Adult
Antitubercular Agents / pharmacology
Contact Tracing / methods*
Drug Resistance, Multiple, Bacterial*
Extensively Drug-Resistant Tuberculosis / diagnosis*
Extensively Drug-Resistant Tuberculosis / epidemiology
Extensively Drug-Resistant Tuberculosis / microbiology
Extensively Drug-Resistant Tuberculosis / prevention & control
Humans
Mass Screening / methods*
Mycobacterium tuberculosis / classification
Mycobacterium tuberculosis / drug effects
Mycobacterium tuberculosis / genetics*
Population Surveillance
Public Health
United Kingdom / epidemiology
Young Adult

Substances

Antitubercular Agents