Description of the new allele HLA-DQB1*04:03:02

E Longhi; S Frison; M Mantovani; G Carella; A Malagoli; F Poli

doi:10.1111/j.1744-313X.2011.01048.x

Description of the new allele HLA-DQB1*04:03:02

Int J Immunogenet. 2012 Feb;39(1):77-8. doi: 10.1111/j.1744-313X.2011.01048.x. Epub 2011 Oct 21.

Authors

E Longhi¹, S Frison, M Mantovani, G Carella, A Malagoli, F Poli

Affiliation

¹ Dipartimento di Medicina Rigenerativa, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza, Milano, Italy.

PMID: 22017792
DOI: 10.1111/j.1744-313X.2011.01048.x

Abstract

A new variant of HLA-DQB1*04:03 allele officially designated as HLA-DQB1*04:03:02 was detected in two unrelated Caucasoid individuals by polymerase chain reaction-sequence-specific primers and SBT. The new allele nucleotide sequence differs from HLA-DQB1*04:03:01 for a single silent point mutation in exon 2 at position 159, codon 21.

MeSH terms

Alleles*
Base Sequence
DNA Primers / genetics
DNA Primers / metabolism
Exons
Female
Genome, Human
HLA-DQ beta-Chains / analysis
HLA-DQ beta-Chains / genetics*
HLA-DQ beta-Chains / metabolism
Histocompatibility Testing
Humans
Point Mutation
White People / genetics*

Substances

DNA Primers
HLA-DQ beta-Chains
HLA-DQB1 antigen