Human cystic echinococcosis in two south-western and central-western Romanian counties: a 7-year epidemiological and clinical overview

Acta Trop. 2012 Jan;121(1):26-9. doi: 10.1016/j.actatropica.2011.10.003. Epub 2011 Oct 12.

Abstract

Purpose: To analyze the epidemiological and clinical characteristics of human cystic echinococcosis (CE) in two Romanian counties, of which one is known from a previous survey as hyperendemic, whereas in the other no extensive studies have been undertaken so far.

Methods: Retrospective investigation of the medical records of the patients diagnosed with this condition and hospitalized during 2004-2010 in Caras-Severin and Hunedoara counties.

Results: A total of 190 patients aged 5-88 years (44.3±21.8 years old) were diagnosed with CE. More than one fifth of cases (21.1%) were younger than 19 years old, indicating active transmission of the disease. The yearly average incidence was 3.3 cases/100,000 inhabitants. The highest incidence was registered in patients aged 60-69 years (6.2 cases/100,000 inhabitants), regardless of their gender. Liver involvement occurred in 84.7% of patients. One fifth of the cases (20%) presented complications. Normal values of the eosinophil counts and leukocyte counts predominated within the study group. The length of the hospital stay varied between 1 and 65 days with a mean of 13.1±9.5 days.

Conclusions: CE has a significant burden in this part of Romania, and continues to be a public health concern. Consequently, better implementation of preventive measures and extensive informative campaigns for the population are mandatory.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Echinococcosis / epidemiology*
  • Echinococcosis / pathology*
  • Endemic Diseases
  • Eosinophils / immunology
  • Female
  • Hospitalization
  • Humans
  • Incidence
  • Length of Stay
  • Leukocyte Count
  • Male
  • Middle Aged
  • Retrospective Studies
  • Romania / epidemiology
  • Young Adult