Polysomnography reveals unexpectedly high rates of organic sleep disorders in patients with prediagnosed primary insomnia

Sleep Breath. 2012 Dec;16(4):1097-103. doi: 10.1007/s11325-011-0608-8. Epub 2011 Oct 25.

Abstract

Objective: It is a matter of debate whether patients with primary insomnia require a polysomnographic examination in order to exclude specific sleep disorders such as sleep apnea syndrome (SAS) or periodic limb movements (PLM). Using a prospective design, we investigated the prevalence of organic sleep disorders by means of polysomnography (PSG) in a series of patients who were previously diagnosed with primary insomnia. This diagnosis was based on a clinical exam and an ambulatory monitoring device or previous PSG.

Methods: Seventy-seven women and 16 men (mean age 55.12 ± 13.21 years) who were admitted for cognitive behavioral therapy for insomnia were evaluated by PSG including cardiorespiratory parameters and tibialis EMG. Among them, 50 patients had undergone a clinical exam by a sleep specialist; in 18 patients, actigraphy or portable monitoring had been performed to exclude SAS or PLM; 25 patients had undergone PSG in another sleep lab previously.

Results: In 32 patients (34% of the sample), a PSG revealed a specific sleep disorder (SAS 16; PLMD 11; both 5), resulting in therapeutic consequences for 21 patients (SAS 10; PLMD 9; both 2). SAS and PLM patients were older and SAS patients had a higher body mass index than insomnia patients without additional findings.

Conclusion: Indications for a PSG should be handled less restrictively in the diagnostic workup of older insomnia patients since they have a higher risk of comorbid sleep disorders even in the absence of the clinical signs of SAS or PLM.

MeSH terms

  • Adult
  • Aged
  • Cognitive Behavioral Therapy
  • Comorbidity
  • Cross-Sectional Studies
  • Depressive Disorder / diagnosis
  • Depressive Disorder / epidemiology
  • Depressive Disorder / therapy
  • Disorders of Excessive Somnolence / diagnosis
  • Disorders of Excessive Somnolence / epidemiology
  • Disorders of Excessive Somnolence / therapy
  • Female
  • Humans
  • Male
  • Mass Screening
  • Middle Aged
  • Nocturnal Myoclonus Syndrome / diagnosis
  • Nocturnal Myoclonus Syndrome / epidemiology
  • Nocturnal Myoclonus Syndrome / therapy
  • Polysomnography*
  • Risk Factors
  • Sleep Apnea, Obstructive / diagnosis
  • Sleep Apnea, Obstructive / epidemiology
  • Sleep Apnea, Obstructive / therapy
  • Sleep Initiation and Maintenance Disorders / diagnosis*
  • Sleep Initiation and Maintenance Disorders / epidemiology*
  • Sleep Initiation and Maintenance Disorders / therapy
  • Sleep Wake Disorders / diagnosis*
  • Sleep Wake Disorders / epidemiology*
  • Sleep Wake Disorders / therapy