UV-responsive polymeric superamphiphile based on a complex of malachite green derivative and a double hydrophilic block copolymer

Langmuir. 2011 Dec 6;27(23):14108-11. doi: 10.1021/la203486q. Epub 2011 Nov 8.

Abstract

We have prepared a UV-responsive polymeric superamphiphile, formed by a malachite green derivative and the double hydrophilic block copolymer methoxy-poly(ethylene glycol)(114)-block-poly(l-lysine hydrochloride)(200) (PEG-b-PLKC) on the basis of electrostatic interactions. The malachite green derivative undergoes photo-ionization upon UV irradiation, which makes it more hydrophilic, resulting in changes in the self-assembly behavior of the polymeric superamphiphile. For this reason, the polymeric superamphiphile originally self-assembles to form sheetlike aggregates, which disassemble after UV irradiation because of the increased solubility of the malachite green derivative. By use of Nile red as a probe, the polarity of the polymeric superamphiphile solution is confirmed to be increased after UV irradiation by fluorescence spectra, which also explains the disassembly of the polymeric superamphiphile.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Hydrophobic and Hydrophilic Interactions
  • Lysine / analogs & derivatives*
  • Lysine / chemistry
  • Models, Molecular
  • Polyethylene Glycols / chemistry*
  • Ultraviolet Rays*

Substances

  • poly(ethylene glycol) lysine copolymer
  • Polyethylene Glycols
  • Lysine