Carotid intima-media thickness, but not visceral fat area or adiponectin, correlates with intracoronary stenosis detected by multislice computed tomography in people with type 2 diabetes and hypertension

Tomoko Nakanishi-Minami; Ken Kishida; Yasuhiko Nakagawa; Hideaki Nakatsuji; Yohei Kuroda; Yukiyoshi Okauchi; Keita Yamasaki; Yuhei Nojima; Kenichi Tsujii; Masahiro Kumada; Kou-ichi Tachibana; Tadashi Nakamura; Satoru Sumitsuji; Tohru Funahashi; Iichiro Shimomura

doi:10.1016/j.diabres.2011.10.022

Carotid intima-media thickness, but not visceral fat area or adiponectin, correlates with intracoronary stenosis detected by multislice computed tomography in people with type 2 diabetes and hypertension

Diabetes Res Clin Pract. 2012 Jan;95(1):e23-6. doi: 10.1016/j.diabres.2011.10.022. Epub 2011 Nov 8.

Authors

Tomoko Nakanishi-Minami¹, Ken Kishida, Yasuhiko Nakagawa, Hideaki Nakatsuji, Yohei Kuroda, Yukiyoshi Okauchi, Keita Yamasaki, Yuhei Nojima, Kenichi Tsujii, Masahiro Kumada, Kou-ichi Tachibana, Tadashi Nakamura, Satoru Sumitsuji, Tohru Funahashi, Iichiro Shimomura

Affiliation

¹ Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.

PMID: 22071433
DOI: 10.1016/j.diabres.2011.10.022

Abstract

We investigated the relationship between intracoronary stenosis detected by multislice computed tomography and various clinical parameters in type 2 diabetic patients with hypertension treated with candesartan (n=42). The results showed that carotid intima-media thickness, but not visceral fat area or adiponectin, correlated significantly with intracoronary stenosis (p<0.05).

MeSH terms

Adiponectin / blood*
Aged
Carotid Intima-Media Thickness*
Coronary Stenosis / complications*
Coronary Stenosis / diagnostic imaging*
Coronary Stenosis / physiopathology
Diabetes Mellitus, Type 2 / complications*
Diabetes Mellitus, Type 2 / diagnostic imaging
Female
Humans
Hypertension / complications*
Hypertension / diagnostic imaging
Intra-Abdominal Fat / diagnostic imaging
Intra-Abdominal Fat / physiopathology*
Male
Middle Aged
Multidetector Computed Tomography

Substances

Adiponectin