Evaluation of Neisseria gonorrhoeae multiple-locus variable-number tandem-repeat analysis, N. gonorrhoeae Multiantigen sequence typing, and full-length porB gene sequence analysis for molecular epidemiological typing

J Clin Microbiol. 2012 Jan;50(1):180-3. doi: 10.1128/JCM.05386-11. Epub 2011 Nov 9.

Abstract

The performance characteristics of Neisseria gonorrhoeae multilocus variable-number tandem-repeat analysis were evaluated, by comparison with N. gonorrhoeae multiantigen sequence typing and full-length porB sequence typing. Assessment of the relatedness of intra- and interpatient isolates showed that all three genotyping techniques display a high resolution and typeability.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antigens, Bacterial / genetics
  • Cluster Analysis
  • DNA, Bacterial / genetics
  • Female
  • Genotype
  • Humans
  • Male
  • Minisatellite Repeats
  • Molecular Epidemiology / methods*
  • Molecular Typing / methods*
  • Neisseria gonorrhoeae / classification*
  • Neisseria gonorrhoeae / genetics*
  • Porins / genetics
  • Sequence Analysis

Substances

  • Antigens, Bacterial
  • DNA, Bacterial
  • Porins
  • porin protein, Neisseria