Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4)

J Med Chem. 2012 Feb 9;55(3):977-94. doi: 10.1021/jm200568c. Epub 2011 Dec 2.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-HIV Agents / pharmacology
  • Anti-HIV Agents / therapeutic use
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Arthritis, Rheumatoid / drug therapy
  • Asthma / drug therapy
  • Cell Movement
  • Drug Discovery
  • HIV-1 / drug effects
  • HIV-1 / physiology
  • Hematologic Neoplasms / drug therapy
  • Hematologic Neoplasms / pathology
  • Humans
  • Neoplasm Invasiveness
  • Receptors, CXCR4 / agonists*
  • Receptors, CXCR4 / antagonists & inhibitors*
  • Receptors, CXCR4 / physiology*
  • Stem Cells / drug effects
  • Stem Cells / physiology
  • Virus Internalization / drug effects

Substances

  • Anti-HIV Agents
  • Anti-Inflammatory Agents
  • Antineoplastic Agents
  • Receptors, CXCR4