Abstract
Immunoelectron microscopy demonstrated the presence of Pf155/RESA in dense granules of Plasmodium falciparum merozoites rather than in micronemes as previously suggested. Since the dense granules are released after the merozoite enters the parasitophorous vacuole, the role of Pf155/RESA in invasion and subsequent steps of parasite development may differ from that of a molecule located in the micronemes.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Antigens, Protozoan / analysis*
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Antigens, Surface / analysis*
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Cross Reactions
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Cytoplasmic Granules / immunology*
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Cytoplasmic Granules / ultrastructure
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Microscopy, Immunoelectron
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Plasmodium falciparum / immunology*
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Plasmodium falciparum / ultrastructure
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Protozoan Proteins / analysis*
Substances
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Antigens, Protozoan
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Antigens, Surface
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Protozoan Proteins
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ring-infected erythrocyte surface antigen (RESA), Plasmodium falciparum