Abstract
The asymmetric hydrovinylation (1 mol % Ni-cat., 1 atm, ethylene, >98% ee) products from 1-methylenetetralines are readily converted into 3,3-disubstituted oxindoles and subsequently to pyrrolidinoindolines. These hydrovinylation products are also useful for the syntheses of enantiopure benzomorphans.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Catalysis
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Ethylenes / chemistry*
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Indoles / chemistry*
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Molecular Structure
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Oxindoles
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Pyrrolidines / chemical synthesis*
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Pyrrolidines / chemistry
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Stereoisomerism
Substances
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Ethylenes
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Indoles
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Oxindoles
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Pyrrolidines
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2-oxindole
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ethylene