Treatment of Kimura disease with intravenous immunoglobulin

Pediatrics. 2011 Dec;128(6):e1633-5. doi: 10.1542/peds.2010-1623. Epub 2011 Nov 21.

Abstract

Kimura disease is an uncommon chronic inflammatory condition of unknown etiology and is characterized by painless subcutaneous nodules, usually affecting the head and neck, eosinophilia, and markedly elevated immunoglobulin E levels. Several reports have described the main modalities of treatment; both corticosteroids and surgery have provided good results, but occasionally corticosteroids cannot be tapered as the disease flares up. We report here the case of an 8-year-old boy diagnosed with Kimura disease who was successfully treated with 1 dose of intravenous immunoglobulin as a steroid-sparing agent.

Publication types

  • Case Reports

MeSH terms

  • Angiolymphoid Hyperplasia with Eosinophilia / drug therapy*
  • Child
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use*
  • Immunologic Factors / therapeutic use*
  • Male

Substances

  • Immunoglobulins, Intravenous
  • Immunologic Factors