Invasive candidiasis following liver transplantation and surgical complications

Mycoses. 2011 Dec:54 Suppl 4:4-7. doi: 10.1111/j.1439-0507.2011.02135.x.

Abstract

The following case report describes a patient with acute liver failure who presented in multiple organ failure and required emergency liver transplantation. A complicated postoperative course lead to sepsis which did not respond to conventional anti bacterial therapy. Despite antifungal prophylaxis with an azole invasive candidiasis was diagnosed and the patient was successfully treated with anidulafungin. The difficulties in diagnosis and treatment of invasive fungal infections in this population are highlighted.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anidulafungin
  • Antifungal Agents / administration & dosage
  • Candidiasis, Invasive / diagnosis*
  • Candidiasis, Invasive / drug therapy
  • Candidiasis, Invasive / microbiology*
  • Echinocandins / administration & dosage
  • Humans
  • Immunocompromised Host
  • Liver Failure / surgery
  • Liver Transplantation / adverse effects*
  • Male
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / drug therapy
  • Postoperative Complications / microbiology*
  • Treatment Outcome

Substances

  • Antifungal Agents
  • Echinocandins
  • Anidulafungin