Chronic thromboembolic pulmonary hypertension due to upper-extremity deep vein thrombosis caused by thoracic outlet syndrome

Arch Bronconeumol. 2012 Feb;48(2):61-3. doi: 10.1016/j.arbres.2011.05.006. Epub 2011 Dec 3.
[Article in English, Spanish]

Abstract

We report on a 20 year-old woman diagnosed with pulmonary embolism (PE) and right subclavian vein thrombosis attributable to stasis caused by right clavicular prominence. At the 10-months follow-up, the patient had developed chronic thromboembolic pulmonary hypertension (CTEPH), and treatment was begun with a dual endothelin receptor antagonist. Very few cases of deep venous thrombosis of upper limb have been reported in relation to anatomical abnormalities. This case is also exceptional because the patient developed a chronic thromboembolic pulmonary hypertension, whose incidence is estimated at 0.5% of all symptomatic PE.

Publication types

  • Case Reports

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Arm / blood supply*
  • Asthma / complications
  • Bosentan
  • Cardiac Catheterization
  • Dyspnea / etiology
  • Female
  • Humans
  • Hypertension, Pulmonary / etiology*
  • Pulmonary Embolism / etiology*
  • Smoking / adverse effects
  • Sulfonamides / therapeutic use
  • Syncope / etiology
  • Thoracic Outlet Syndrome / complications*
  • Thrombophlebitis / etiology*
  • Young Adult

Substances

  • Antihypertensive Agents
  • Sulfonamides
  • Bosentan