Cell therapies for liver diseases

Liver Transpl. 2012 Jan;18(1):9-21. doi: 10.1002/lt.22467.

Abstract

Cell therapies, which include bioartificial liver support and hepatocyte transplantation, have emerged as potential treatments for a variety of liver diseases. Acute liver failure, acute-on-chronic liver failure, and inherited metabolic liver diseases are examples of liver diseases that have been successfully treated with cell therapies at centers around the world. Cell therapies also have the potential to be widely applied to other liver diseases, including noninherited liver diseases and liver cancer, and to improve the success of liver transplantation. Here we briefly summarize current concepts of cell therapy for liver diseases.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell- and Tissue-Based Therapy / methods*
  • Disease Models, Animal
  • Hepatocytes / transplantation
  • Humans
  • Liver Diseases / therapy*
  • Liver, Artificial
  • Stem Cell Transplantation / methods
  • Swine