Abstract
We compared the effect of plasmapheresis on antineuronal autoantibody titers in the serum and CSF of 3 patients with CNS paraneoplastic syndromes. Plasmapheresis reduced the serum autoantibody titer to 20% of the initial levels in the 3 patients, but the CSF autoantibody titer decreased only in the patient with severe damage of the blood-brain barrier.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Autoantibodies / analysis*
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Autoantibodies / cerebrospinal fluid
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Central Nervous System Diseases / immunology*
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Central Nervous System Diseases / therapy
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Female
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Humans
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Male
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Middle Aged
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Paraneoplastic Syndromes / immunology*
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Paraneoplastic Syndromes / therapy
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Plasmapheresis*
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Time Factors