Abstract
The 7-valent pneumococcal conjugate vaccine (PCV7) reduces carriage of vaccine type Streptococcus pneumoniae but leads to replacement by nonvaccine serotypes and may affect carriage of other respiratory pathogens. We investigated nasopharyngeal carriage of S. pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Fijian infants participating in a pneumococcal vaccine trial using quantitative PCR. Vaccination did not affect pathogen carriage rates or densities, whereas significant differences between the two major ethnic groups were observed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Infections / epidemiology*
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Bacterial Infections / microbiology
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Carrier State / epidemiology*
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Carrier State / microbiology
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Child
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Child, Preschool
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Fiji / epidemiology
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Gram-Negative Bacteria / isolation & purification*
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Gram-Positive Bacteria / isolation & purification*
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Heptavalent Pneumococcal Conjugate Vaccine
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Humans
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Infant
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Nasopharynx / microbiology*
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Pneumococcal Vaccines / administration & dosage*
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Prevalence
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Vaccination / statistics & numerical data*
Substances
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Heptavalent Pneumococcal Conjugate Vaccine
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Pneumococcal Vaccines