[Risk factors of post-asphyxial multiple organ dysfunction in neonates]

Jun-Yan Liu; Tao Xiong; Hong Feng; Yi Qu; Qiang-Hua Ye; De-Zhi Mu

[Risk factors of post-asphyxial multiple organ dysfunction in neonates]

Zhongguo Dang Dai Er Ke Za Zhi. 2011 Dec;13(12):940-3.

[Article in Chinese]

Authors

Jun-Yan Liu¹, Tao Xiong, Hong Feng, Yi Qu, Qiang-Hua Ye, De-Zhi Mu

Affiliation

¹ Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu 610041, China.

PMID: 22172254

Abstract

Objective: To investigate the risk factors related to post-asphyxial multiple organ dysfunction (PA-MOD) in neonates.

Methods: A total of 397 neonates with birth asphyxia were enrolled from January 2009 to December 2010.The patients were divided into PA-MOD group (n=179) and non-PA-MOD group (n=218). The risk factors of PA-MOD were retrospectively studied.

Results: Multivariate logistic regression analysis showed that severe asphyxia, fetal distress, abnormal labor, and decreased amniotic fluid were the risk factors for PA-MOD among the neonates. Spearman rank correlation analysis showed that the number of the involved organs increased along with the increase of age at admission (P<0.05) and with the decrease of gestational age and birth weight (P<0.05).

Conclusions: The efforts should be made to enhance perinatal care for neonates, especially for preterm infants and low-birh-weight infants, to decrease the incidence of MOD.

Publication types

English Abstract
Research Support, Non-U.S. Gov't

MeSH terms

Asphyxia Neonatorum / complications*
Female
Humans
Infant, Newborn
Logistic Models
Male
Multiple Organ Failure / etiology*
Multiple Organ Failure / prevention & control
Risk Factors