Local vs. systemic mononuclear phagocytes in age-related macular degeneration and their regulation by CCL2-CCR2 and CX3CL1-CX3CR1 chemokine signalling

Adv Exp Med Biol. 2012:723:17-22. doi: 10.1007/978-1-4614-0631-0_3.
No abstract available

Publication types

  • Review

MeSH terms

  • CX3C Chemokine Receptor 1
  • Chemokine CCL2 / genetics
  • Chemokine CCL2 / immunology*
  • Chemokine CCL2 / metabolism
  • Chemokine CX3CL1 / genetics
  • Chemokine CX3CL1 / immunology*
  • Chemokine CX3CL1 / metabolism
  • Humans
  • Leukocytes, Mononuclear / immunology
  • Leukocytes, Mononuclear / metabolism
  • Macular Degeneration / immunology*
  • Macular Degeneration / metabolism
  • Phagocytes / immunology
  • Phagocytes / metabolism
  • Receptors, CCR2 / genetics
  • Receptors, CCR2 / immunology*
  • Receptors, CCR2 / metabolism
  • Receptors, Chemokine / genetics
  • Receptors, Chemokine / immunology*
  • Receptors, Chemokine / metabolism
  • Signal Transduction / immunology

Substances

  • CCL2 protein, human
  • CCR2 protein, human
  • CX3C Chemokine Receptor 1
  • CX3CL1 protein, human
  • CX3CR1 protein, human
  • Chemokine CCL2
  • Chemokine CX3CL1
  • Receptors, CCR2
  • Receptors, Chemokine