Gene augmentation trials using the Rpe65-deficient dog: contributions towards development and refinement of human clinical trials

Adv Exp Med Biol. 2012:723:177-82. doi: 10.1007/978-1-4614-0631-0_24.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Carrier Proteins / genetics*
  • Clinical Trials, Phase I as Topic / methods
  • Clinical Trials, Phase II as Topic / methods
  • Disease Models, Animal*
  • Dogs*
  • Eye Proteins / genetics*
  • Genetic Therapy / methods*
  • Humans
  • Leber Congenital Amaurosis / genetics*
  • Leber Congenital Amaurosis / immunology
  • Leber Congenital Amaurosis / therapy*
  • cis-trans-Isomerases

Substances

  • Carrier Proteins
  • Eye Proteins
  • retinoid isomerohydrolase
  • cis-trans-Isomerases