Precursor T-Cell acute lymphoblastic leukemia/lymphoma with rare presentation in the urinary bladder

Hematol Rep. 2011 Aug 31;3(2):e18. doi: 10.4081/hr.2011.e18. Epub 2011 Oct 20.

Abstract

We present the 16th reported case of Acute Lymphoblastic Leukemia (ALL) with involvement in the bladder. Our patient was a 22 year-old man with T-cell ALL with a mediastinal mass. He received hyperfractionated cyclophos-phamide, vincristine, doxorubicin, dexamethasone (HyperCVAD) with mediastinal radiation. Prior to starting maintenance, he relapsed in the bladder and marrow. He received a nelarabine-based induction regimen and achieved remission. This was followed by an unrelated 11/12 HLA-matched myeloablative allogeneic stem cell transplant. He is in complete remission for the past 409 days.

Keywords: allogeneic stem cell transplantation.; bladder involvement; precursor t-cell acute lymphoblastic leukemia/lymphoma.

Publication types

  • Case Reports