Cytomegalovirus: recent progress in understanding pathogenesis and control

QJM. 2012 May;105(5):401-5. doi: 10.1093/qjmed/hcr262. Epub 2011 Dec 22.

Abstract

Cytomegalovirus continues to be an important pathogen in a variety of patient groups especially the neonate and the transplant recipient, and has implicated in a range of pathologies including inflammatory disease and in contributing to early death in ageing populations. This review will focus on advances in understanding the virus-host interaction and options for the new therapeutic control measures.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiviral Agents / therapeutic use
  • CD4-Positive T-Lymphocytes / physiology
  • CD8-Positive T-Lymphocytes / physiology
  • Cytomegalovirus / immunology
  • Cytomegalovirus / pathogenicity*
  • Cytomegalovirus Infections / prevention & control
  • Cytomegalovirus Infections / virology*
  • Cytomegalovirus Vaccines
  • Humans
  • Immunocompromised Host
  • Viral Load

Substances

  • Antiviral Agents
  • Cytomegalovirus Vaccines