htSeqTools: high-throughput sequencing quality control, processing and visualization in R

Bioinformatics. 2012 Feb 15;28(4):589-90. doi: 10.1093/bioinformatics/btr700. Epub 2011 Dec 22.

Abstract

We provide a Bioconductor package with quality assessment, processing and visualization tools for high-throughput sequencing data, with emphasis in ChIP-seq and RNA-seq studies. It includes detection of outliers and biases, inefficient immuno-precipitation and overamplification artifacts, de novo identification of read-rich genomic regions and visualization of the location and coverage of genomic region lists.

Availability: www.bioconductor.org.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genomics
  • High-Throughput Nucleotide Sequencing / methods*
  • Humans
  • Internet
  • Oligonucleotide Array Sequence Analysis
  • Quality Control
  • Saccharomyces cerevisiae / genetics
  • Software*