[Detection and management of non-motor symptoms in Parkinson's disease: impact on their prevalence]

Rev Med Chil. 2011 Aug;139(8):1032-8. Epub 2011 Dec 20.
[Article in Spanish]

Abstract

Background: Non-motor symptoms are common among patients with Parkinson disease and include cognitive, psychiatric, sleep and autonomic dysfunctions.

Aim: To determine if the detection of non-motor symptoms along with the appropriate referral to an specialist has an impact on their prevalence after one year follow-up.

Material and methods: We included 60 patients diagnosed with Parkinson's disease attending to the Movement Disorder Clinic. The presence of non-motor symptoms was determined by the non-motor symptom questionnaire (NMSQuest).

Results: The mean NMSQuest scores at baseline and at one year follow up were 12.6 ± 6.2 and 9.9 ± 5.6, respectively (p < 0.01). The non-motor symptoms that showed a statistically significant differences in frequency between baseline and the final assessment, were constipation (p = 0.04), urinary urgency (p = 0.02), hallucinations (p = 0.04), dizziness (p = 0.02) and vivid dreams (p = 0.04).

Conclusions: Intentional search for non-motor symptoms in patients with Parkinson's disease along with a multidisciplinary approach has an impact on their prevalence. The change in specific symptoms is probably related to adjustments in dopaminergic management.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Dopamine / administration & dosage*
  • Dopamine Agents / administration & dosage*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Motor Activity* / drug effects
  • Movement Disorders / diagnosis
  • Movement Disorders / epidemiology*
  • Parkinson Disease / complications*
  • Parkinson Disease / drug therapy
  • Surveys and Questionnaires / standards

Substances

  • Dopamine Agents
  • Dopamine