Respiratory disease in common variable immunodeficiency and other primary immunodeficiency disorders

F A Hampson; A Chandra; N J Screaton; A Condliffe; D S Kumararatne; A R Exley; J L Babar

doi:10.1016/j.crad.2011.10.028

Respiratory disease in common variable immunodeficiency and other primary immunodeficiency disorders

Clin Radiol. 2012 Jun;67(6):587-95. doi: 10.1016/j.crad.2011.10.028. Epub 2012 Jan 9.

Authors

F A Hampson¹, A Chandra, N J Screaton, A Condliffe, D S Kumararatne, A R Exley, J L Babar

Affiliation

¹ Department of Radiology, Papworth Hospital, Papworth Everard, Cambridge, UK.

PMID: 22226567
DOI: 10.1016/j.crad.2011.10.028

Abstract

Respiratory disease is a significant cause of morbidity and mortality amongst patients with primary immunodeficiency disorders. Computed tomography (CT) plays an important role in the multidisciplinary approach to these conditions, in detecting, characterizing, and quantifying the extent of lung damage and in directing treatment. The aim of this review is to classify the primary immunodeficiency disorders and describe the thoracic complications and the associated CT findings whilst discussing the role of radiology in diagnosis and surveillance.

Publication types

Review

MeSH terms

Adult
Common Variable Immunodeficiency / complications
Common Variable Immunodeficiency / diagnostic imaging*
Diagnosis, Differential
Female
Humans
Immunologic Deficiency Syndromes / complications
Immunologic Deficiency Syndromes / diagnostic imaging
Lung / diagnostic imaging
Male
Middle Aged
Respiratory Tract Diseases / complications
Respiratory Tract Diseases / diagnostic imaging*
Tomography, X-Ray Computed / methods