Abstract
Patients with celiac disease have an increased risk for severe influenza infection and they show less of a response to certain vaccine types. During the influenza A/H1N1/09 pandemic, we prospectively investigated pandemic vaccine responses in 14 pediatric patients with celiac disease and age-/sex-matched controls. All of the children with celiac disease reached protective antibody titers (≥40) and showed a geometric mean titer comparable with the control group (530 vs 573).
Trial registration:
ClinicalTrials.gov NCT01022905.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Antibody Formation*
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Case-Control Studies
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Celiac Disease / complications
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Celiac Disease / immunology*
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Child
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Child, Preschool
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Disease Susceptibility
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Female
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Humans
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Influenza A Virus, H1N1 Subtype*
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Influenza Vaccines / immunology*
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Influenza, Human / epidemiology
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Influenza, Human / immunology
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Influenza, Human / prevention & control*
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Influenza, Human / virology
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Male
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Pandemics
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Prospective Studies
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Risk Factors
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Vaccination*
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Young Adult
Associated data
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ClinicalTrials.gov/NCT01022905