Abstract
The role of isocitrate dehydrogenase mutations as a therapeutic target for cancer therapy is examined.
MeSH terms
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Bile Duct Neoplasms / genetics*
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Bile Ducts, Intrahepatic / pathology*
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Cholangiocarcinoma / genetics*
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Female
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Gallbladder Neoplasms / genetics*
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Humans
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Isocitrate Dehydrogenase / genetics*
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Male
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Mutation*
Substances
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IDH2 protein, human
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Isocitrate Dehydrogenase
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IDH1 protein, human