Abstract
Two new iridoids, jatamanvaltrates N (1) and O (2), together with four known compounds (3-6), were isolated from the roots of Valeriana jatamansi. Their structures and relative configurations were elucidated by spectroscopic methods (IR, ESI-MS, HR-ESI-MS, 1D, and 2D NMR) and by comparison of their NMR spectral data with those of related compounds. All the isolated compounds were evaluated for their neuroprotective effects, and only compound 1 showed weak neuroprotective activities.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Iridoids / chemistry
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Iridoids / isolation & purification*
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Iridoids / pharmacology
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Molecular Structure
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Neuroprotective Agents / chemistry
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Neuroprotective Agents / isolation & purification*
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Neuroprotective Agents / pharmacology
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Nuclear Magnetic Resonance, Biomolecular
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Plant Roots / chemistry
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Valerian / chemistry*
Substances
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Drugs, Chinese Herbal
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Iridoids
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Neuroprotective Agents
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jatamanvaltrate N
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jatamanvaltrate O