Tantalum oxide/carbon nanotubes composite coatings on titanium, and their functionalization with organophosphonic molecular films: a high quality scaffold for hydroxyapatite growth

J Colloid Interface Sci. 2012 Apr 1;371(1):150-8. doi: 10.1016/j.jcis.2011.12.066. Epub 2012 Jan 8.

Abstract

Nowadays, titanium is a very commonly used biomaterial for the preparation of orthopedic and dental implants. Its excellent mechanical and biochemical bulk properties are nevertheless counterbalanced by its propensity to long term degradation in physiological conditions and its weak osseointegrative capacities. In this context, surface modifications can significantly hinder titanium weaknesses. The approach considered in this work relies on the preparation of thin composite coatings based on tantalum oxide and carbon nanotubes by sol-gel process. Tantalum is particularly interesting for its high biocompatibility and bioactivity, as well as its strong resistance to bio-corrosion. Carbon nanotubes are exploited to reinforce the compactness and homogeneity of the coatings, and can act as a favorable factor to strengthen the interaction with bone components by biomimicry. The composite layers are further modified with specific organophosphonic acid molecular films, able to chemically bind the tantalum oxide surface and improve the hydroxyapatite formation process. The characteristics and the qualities of these hybrid inorganic/organic coatings are evaluated by XPS, SEM, TEM, peeling tests, contact angle measurements, and electrochemical characterizations (free potential, polarization curves).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials / chemistry*
  • Biocompatible Materials / metabolism
  • Durapatite / chemistry*
  • Durapatite / metabolism
  • Materials Testing
  • Nanotubes, Carbon / chemistry*
  • Organophosphonates / metabolism*
  • Organophosphorus Compounds / chemistry*
  • Organophosphorus Compounds / metabolism
  • Oxides / chemistry*
  • Oxides / metabolism
  • Phase Transition
  • Surface Properties
  • Tantalum / chemistry*
  • Tantalum / metabolism
  • Titanium / chemistry*
  • Titanium / metabolism

Substances

  • Biocompatible Materials
  • Nanotubes, Carbon
  • Organophosphonates
  • Organophosphorus Compounds
  • Oxides
  • Tantalum
  • Durapatite
  • Titanium
  • tantalum oxide