Scopolamine usually is found to impair various aspects of human cognitive performance. Recently, however, a significant (though modest) improvement in verbal fluency has been reported following scopolamine hydrobromide (0.6 and 1.2 mg p.o.). This study replicated that effect, finding significantly better FAS letter fluency in contrast to poorer performance on other neuropsychological measures following sub cutaneous injection of 0.4 mg scopolamine. Data are discussed in terms of a functional state model of drug action.