First human isolate of Salmonella enterica serotype Enteritidis harboring blaCTX-M-14 in South America

Antimicrob Agents Chemother. 2012 Apr;56(4):2132-4. doi: 10.1128/AAC.05530-11. Epub 2012 Jan 30.

Abstract

We studied a clinical isolate of Salmonella enterica serotype Enteritidis showing resistance to oxyiminocephalosporins. PCR analysis confirmed the presence of bla(CTX-M-14) linked to IS903 in a 95-kb IncI1 conjugative plasmid. Such a plasmid is maintained on account of the presence of a pndAC addiction system. Multilocus sequence typing (MLST) analysis indicated that the strain belongs to ST11. This is the first report of bla(CTX-M-14) in Salmonella Enteritidis of human origin in South America.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anti-Bacterial Agents / pharmacology
  • Cephalosporin Resistance / genetics
  • Conjugation, Genetic
  • Female
  • Humans
  • Kidney Failure, Chronic / complications
  • Microbial Sensitivity Tests
  • Plasmids / genetics
  • Polymerase Chain Reaction
  • Salmonella Infections / microbiology*
  • Salmonella enteritidis / drug effects*
  • Salmonella enteritidis / genetics*
  • South America
  • Uruguay
  • beta-Lactamases / genetics*

Substances

  • Anti-Bacterial Agents
  • beta-lactamase CTX-M-14
  • beta-Lactamases