Saccharomyces boulardii reduces infection intensity of mice with toxocariasis

Luciana Farias da Costa de Avila; Fabricio Rochedo Conceição; Paula de Lima Telmo; Gisele Ferreira Dutra; Diego Gil de los Santos; Lourdes Helena Rodrigues Martins; Maria Elisabeth Aires Berne; Pedro Eduardo Almeida da Silva; Carlos James Scaini

doi:10.1016/j.vetpar.2012.01.002

Saccharomyces boulardii reduces infection intensity of mice with toxocariasis

Vet Parasitol. 2012 Jun 8;187(1-2):337-40. doi: 10.1016/j.vetpar.2012.01.002. Epub 2012 Jan 8.

Authors

Luciana Farias da Costa de Avila¹, Fabricio Rochedo Conceição, Paula de Lima Telmo, Gisele Ferreira Dutra, Diego Gil de los Santos, Lourdes Helena Rodrigues Martins, Maria Elisabeth Aires Berne, Pedro Eduardo Almeida da Silva, Carlos James Scaini

Affiliation

¹ Post-Graduate Program in Health Sciences - Parasitology Laboratory, Universidade Federal do Rio Grande (FURG), Academic Area of University Hospital - FURG, Brazil. [email protected]

PMID: 22305116
DOI: 10.1016/j.vetpar.2012.01.002

Abstract

Several studies have shown the benefit of the use of probiotics in the prevention and treatment of diseases; however, few of them have investigated the effect of probiotics on parasitosis. In this study, the effect of Saccharomyces boulardii on the intensity of infection of mice with toxocariasis was evaluated. The animals were fed with a diet supplemented with S. boulardii for 15 days before inoculation with Toxocara canis eggs and for 2 or 60 days post-inoculation. S. boulardii promoted a reduction of approximately 36% in the average number of recovered T. canis larvae, suggesting that it can be used as an alternative to help control toxocariasis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Female
Mice
Probiotics / therapeutic use*
Saccharomyces*
Toxocara canis
Toxocariasis / therapy*