[Atypical polypoid adenomyoma: retrospective study about 8 cases from Jeanne-de-Flandre Hospital between 1996 and 2008]

Gynecol Obstet Fertil. 2014 Feb;42(2):84-91. doi: 10.1016/j.gyobfe.2011.08.003. Epub 2012 Feb 4.
[Article in French]

Abstract

Objectives: To propose a therapeutic approach and follow-up of patients with atypical polypoid adenomyoma (APA) wishing to remain fertile.

Patients and method: We are presenting a retrospective study of eight APA cases.

Results: Two patients immediately received radical treatment, and one patient had an endometrial thermocoagulation. The remaining five patients received a conservative treatment with ultrasound and hysteroscopic monitoring. Among them, two had full-term pregnancies, one is being treated for infertility, in one case, the APA disappeared after three hysteroscopy-curettages and macroprogestative treatment. Lastly, one of our patients died from an aggressive endometrioid ovarian bilateral tumour associated with an endometrial adenocarcinoma.

Discussion and conclusion: Radical treatment is necessary for cases of APA in women no longer wishing to remain fertile. For those wishing to remain fertile, we can offer a conservative treatment once they have been informed regarding the associated risk of relapse, degeneration, and ovarian lesions which necessitate stricter follow-up.

Keywords: Adénocarcinome endométrial; Adénomyome polypoïde atypique; Atypical polypoid adenomyoma; Conservative treatment; Endometrial adenocarcinoma; Infertility; Infertilité; Traitement conservateur.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adenomyoma / pathology
  • Adenomyoma / surgery
  • Adenomyoma / therapy*
  • Adult
  • Endometrial Neoplasms / pathology
  • Endometrial Neoplasms / surgery
  • Endometrial Neoplasms / therapy*
  • Fatal Outcome
  • Female
  • Fertility Preservation
  • Humans
  • Hysteroscopy
  • Middle Aged
  • Pregnancy
  • Progestins / therapeutic use
  • Retrospective Studies
  • Risk Factors

Substances

  • Progestins