Genetic defects in PRC2 components other than EZH2 are not common in myeloid malignancies

Blood. 2012 Feb 2;119(5):1318-9. doi: 10.1182/blood-2011-07-365213.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carrier Proteins / genetics*
  • Cohort Studies
  • DNA-Binding Proteins / genetics*
  • Enhancer of Zeste Homolog 2 Protein
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Genetic Variation* / physiology
  • Hematologic Neoplasms / genetics*
  • Humans
  • Myelodysplastic Syndromes / genetics
  • Myeloproliferative Disorders / genetics
  • Neoplasm Proteins
  • Nuclear Proteins / genetics*
  • Polycomb Repressive Complex 2
  • Polycomb-Group Proteins
  • Polymorphism, Single Nucleotide
  • Repressor Proteins / genetics*
  • Transcription Factors / genetics*

Substances

  • Carrier Proteins
  • DNA-Binding Proteins
  • EED protein, human
  • Neoplasm Proteins
  • Nuclear Proteins
  • Polycomb-Group Proteins
  • Repressor Proteins
  • SUZ12 protein, human
  • Transcription Factors
  • EZH2 protein, human
  • Enhancer of Zeste Homolog 2 Protein
  • Polycomb Repressive Complex 2