A turn-on fluorogenic probe for detection of MDMA from ecstasy tablets

Chem Commun (Camb). 2012 Mar 21;48(24):2994-6. doi: 10.1039/c2cc17823k. Epub 2012 Feb 7.

Abstract

We report a fluorogenic probe that is able to discriminate a range of primary or secondary biogenic amines and their natural or synthetic mimics, in water or buffer, by means of the turn-on transient generation of green fluorescence, with high quantum yields and low detection limits, thus making the system suitable for the detection of abuse drugs, such as MDMA, from ecstasy tablets.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry
  • Hallucinogens / analysis*
  • Hallucinogens / chemistry
  • Illicit Drugs / analysis*
  • Illicit Drugs / chemistry
  • N-Methyl-3,4-methylenedioxyamphetamine / analysis*
  • N-Methyl-3,4-methylenedioxyamphetamine / chemistry
  • Substance Abuse Detection*
  • Tablets

Substances

  • Fluorescent Dyes
  • Hallucinogens
  • Illicit Drugs
  • Tablets
  • N-Methyl-3,4-methylenedioxyamphetamine