Abstract
We report the first case of extended-spectrum beta-lactamase producing E. coli community-acquired meningitis complicated with multiple aortic mycotic aneurysms. Because of the acute aneurysm expansion with possible impending rupture on 2 abdominal CT scan, the patient underwent prompt vascular surgery and broad spectrum antibiotic therapy but he died of a hemorrhagic shock. Extended-spectrum beta-lactamase producing E. coli was identified from both blood and cerebrospinal fluid culture before vascular treatment. The present case report does not however change the guidelines of Gram negative bacteria meningitis in adults.
MeSH terms
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Aneurysm, Infected / complications
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Aneurysm, Infected / diagnosis*
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Aneurysm, Infected / surgery
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Anti-Bacterial Agents / administration & dosage
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Aortic Aneurysm / complications
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Aortic Aneurysm / diagnosis*
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Aortic Aneurysm / surgery
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Blood / microbiology
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Cerebrospinal Fluid / microbiology
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Community-Acquired Infections / diagnosis*
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Community-Acquired Infections / microbiology
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Escherichia coli / enzymology*
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Escherichia coli / isolation & purification
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Fatal Outcome
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Humans
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Meningitis, Escherichia coli / complications
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Meningitis, Escherichia coli / diagnosis*
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Meningitis, Escherichia coli / microbiology
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Middle Aged
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Radiography, Abdominal
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Tomography, X-Ray Computed
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beta-Lactamases / metabolism*
Substances
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Anti-Bacterial Agents
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beta-Lactamases