Hepatic encephalopathy after transjugular intrahepatic portosystemic shunt

Oliviero Riggio; Silvia Nardelli; Federica Moscucci; Chiara Pasquale; Lorenzo Ridola; Manuela Merli

doi:10.1016/j.cld.2011.12.008

Hepatic encephalopathy after transjugular intrahepatic portosystemic shunt

Clin Liver Dis. 2012 Feb;16(1):133-46. doi: 10.1016/j.cld.2011.12.008. Epub 2012 Jan 4.

Authors

Oliviero Riggio¹, Silvia Nardelli, Federica Moscucci, Chiara Pasquale, Lorenzo Ridola, Manuela Merli

Affiliation

¹ Department of Clinical Medicine, Centre for the Diagnosis and Treatment of Portal Hypertension, Sapienza University of Rome, Viale dell'Università 37, 00185 Rome, Italy.

PMID: 22321469
DOI: 10.1016/j.cld.2011.12.008

Abstract

Transjugular intrahepatic portosystemic shunt (TIPS) has been used for more than 20 years to treat some of the complications of portal hypertension. When TIPS was initially proposed, it was claimed that the optimal calibration of the shunt could allow an adequate reduction of portal hypertension, avoiding, at the same time, the occurrence of hepatic encephalopathy (HE), a neurologic syndrome. However, several clinical observations have shown that HE occurred rather frequently after TIPS, and HE has become an important issue to be taken into consideration in TIPS candidates and a problem to be faced after the procedure.

Publication types

Review

MeSH terms

Hepatic Encephalopathy / etiology*
Hepatic Encephalopathy / physiopathology
Humans
Hypertension, Portal / surgery*
Portasystemic Shunt, Transjugular Intrahepatic / adverse effects*
Recurrence