Effective techniques for protein structure mining

Methods Mol Biol. 2012:857:33-54. doi: 10.1007/978-1-61779-588-6_2.

Abstract

Retrieval and characterization of protein structure relationships are instrumental in a wide range of tasks in structural biology. The classification of protein structures (COPS) is a web service that provides efficient access to structure and sequence similarities for all currently available protein structures. Here, we focus on the application of COPS to the problem of template selection in homology modeling.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Data Mining / methods*
  • Databases, Protein*
  • Models, Molecular
  • Molecular Sequence Data
  • Protein Conformation
  • Proteins / chemistry*
  • Structural Homology, Protein

Substances

  • Proteins