METabolic adaptations in the tumor MYCroenvironment

Shawn M Davidson; Matthew G Vander Heiden

doi:10.1016/j.cmet.2012.01.005

METabolic adaptations in the tumor MYCroenvironment

Cell Metab. 2012 Feb 8;15(2):131-3. doi: 10.1016/j.cmet.2012.01.005.

Authors

Shawn M Davidson¹, Matthew G Vander Heiden

Affiliation

¹ Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

PMID: 22326214
DOI: 10.1016/j.cmet.2012.01.005

Abstract

In this issue of Cell Metabolism, Yuneva et al. (2012) use mouse cancer models to characterize tumor nutrient metabolism in vivo. This study suggests that the metabolic phenotype of cancer cells is not only determined by the mutational status of specific oncogenes but is also influenced by the cell of origin and tumor microenvironment.

Publication types

Comment