Type III hyperlipoproteinemia in a child with hemolytic uremic syndrome

Metabolism. 1990 Nov;39(11):1196-9. doi: 10.1016/0026-0495(90)90094-s.

Abstract

The case of a 6-year-old girl with severe hyperlipoproteinemia and chronic renal failure that developed after hemolytic uremic syndrome (HUS) is reported. The patient was homozygous for apolipoprotein (apo) E2, and her very-low-density lipoprotein (VLDL)-cholesterol/serum-triglyceride (TG) ratio of 0.63 was unusually high. She was consistently diagnosed to have type III hyperlipoproteinemia (HLP). This is the first report of type III HLP in a child with chronic renal disease.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Apolipoprotein E2
  • Apolipoproteins E / genetics
  • Child
  • Female
  • Hemolytic-Uremic Syndrome / complications*
  • Homozygote
  • Humans
  • Hyperlipoproteinemia Type III / blood
  • Hyperlipoproteinemia Type III / complications*
  • Hyperlipoproteinemia Type III / genetics
  • Kidney Failure, Chronic / complications
  • Lipoproteins / blood

Substances

  • Apolipoprotein E2
  • Apolipoproteins E
  • Lipoproteins