Decreased IL-10 production by EBV-transformed B cells from patients with VODI: implications for the pathogenesis of Crohn disease

J Allergy Clin Immunol. 2012 Jun;129(6):1678-80. doi: 10.1016/j.jaci.2012.01.046. Epub 2012 Feb 16.
No abstract available

Publication types

  • Letter

MeSH terms

  • B-Lymphocytes / immunology*
  • B-Lymphocytes / pathology
  • B-Lymphocytes / virology
  • Cell Transformation, Viral
  • Crohn Disease / etiology
  • Germ-Line Mutation
  • Hepatic Veno-Occlusive Disease / immunology*
  • Hepatic Veno-Occlusive Disease / metabolism
  • Herpesvirus 4, Human
  • Homozygote
  • Humans
  • Immunologic Deficiency Syndromes / immunology*
  • Immunologic Deficiency Syndromes / metabolism
  • Interleukin-10 / biosynthesis*
  • Interleukin-10 / genetics
  • Minor Histocompatibility Antigens
  • Nuclear Proteins / genetics

Substances

  • Minor Histocompatibility Antigens
  • Nuclear Proteins
  • Sp110 protein, human
  • Interleukin-10

Supplementary concepts

  • Hepatic venoocclusive disease with immunodeficiency