When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes

Jan Philipp Junker; Alexander van Oudenaarden

doi:10.1016/j.molcel.2012.02.002

When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes

Mol Cell. 2012 Feb 24;45(4):437-8. doi: 10.1016/j.molcel.2012.02.002.

Authors

Jan Philipp Junker¹, Alexander van Oudenaarden

Affiliation

¹ Departments of Physics and Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

PMID: 22365826
DOI: 10.1016/j.molcel.2012.02.002

Abstract

In this issue of Molecular Cell, Stewart-Ornstein et al. (2012) use systematic pair-wise correlation analysis of expression noise in a large number of yeast genes to identify clusters of functionally related genes and signaling pathways responsible for elevated noise.

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