The pharmacogenomics of clopidogrel

World Neurosurg. 2012 Mar-Apr;77(3-4):406-7. doi: 10.1016/j.wneu.2012.02.040. Epub 2012 Feb 11.
No abstract available

Publication types

  • News

MeSH terms

  • Aryl Hydrocarbon Hydroxylases / genetics
  • Clopidogrel
  • Cytochrome P-450 CYP2C19
  • Dose-Response Relationship, Drug
  • Drug Resistance / genetics
  • Heterozygote
  • Humans
  • Pharmacogenetics
  • Platelet Aggregation Inhibitors / pharmacokinetics
  • Platelet Aggregation Inhibitors / pharmacology*
  • Point-of-Care Systems
  • Receptors, Purinergic P2Y12 / genetics
  • Receptors, Purinergic P2Y12 / metabolism
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / pharmacokinetics
  • Ticlopidine / pharmacology

Substances

  • Platelet Aggregation Inhibitors
  • Receptors, Purinergic P2Y12
  • Clopidogrel
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Ticlopidine