[Osteoimmunology - IMMUNOBONE - Understanding the interaction between bone and immune system]

G Schett; T Pap; U Müller-Ladner; T Kamradt

doi:10.1007/s00393-012-0954-3

[Osteoimmunology - IMMUNOBONE - Understanding the interaction between bone and immune system]

Z Rheumatol. 2012 Feb;71(2):138-9. doi: 10.1007/s00393-012-0954-3.

[Article in German]

Authors

G Schett¹, T Pap, U Müller-Ladner, T Kamradt

Affiliation

¹ Medizinische Klinik 3, Rheumatologie & Immunologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinikum Erlangen, Erlangen, Deutschland. [email protected]

PMID: 22370805
DOI: 10.1007/s00393-012-0954-3

Abstract

The special program "Osteoimmunology" under the leadership of the Universities of Erlangen, Jena, Gießen and Münster, is investigating in 27 projects clarification approaches on the causes of inflammatory rheumatic diseases, such as rheumatoid arthritis and ankylosing spondylitis with the aim of developing new forms of treatment. The molecular mechanisms involved in bone damage and the interaction between the immune system and bone and cartilage are topics of research.

Publication types

Review

MeSH terms

Antirheumatic Agents / therapeutic use
Arthritis, Rheumatoid / drug therapy
Arthritis, Rheumatoid / genetics
Arthritis, Rheumatoid / immunology*
Bone and Bones / immunology*
Cartilage / immunology
Humans
Immunogenetic Phenomena / genetics
Immunogenetic Phenomena / immunology
Spondylitis, Ankylosing / drug therapy
Spondylitis, Ankylosing / genetics
Spondylitis, Ankylosing / immunology*
Translational Research, Biomedical
Tumor Necrosis Factor-alpha / antagonists & inhibitors
Tumor Necrosis Factor-alpha / blood

Substances

Antirheumatic Agents
Tumor Necrosis Factor-alpha