Long-term survivors among patients with cancer of unknown primary

Nicholas Pavlidis; Dimitrios Petrakis; Vassilios Golfinopoulos; George Pentheroudakis

doi:10.1016/j.critrevonc.2012.02.002

Long-term survivors among patients with cancer of unknown primary

Crit Rev Oncol Hematol. 2012 Oct;84(1):85-92. doi: 10.1016/j.critrevonc.2012.02.002. Epub 2012 Mar 2.

Authors

Nicholas Pavlidis¹, Dimitrios Petrakis, Vassilios Golfinopoulos, George Pentheroudakis

Affiliation

¹ Department of Medical Oncology, Medical School, University of Ioannina, 451 10 Ioannina, Greece. [email protected]

PMID: 22386806
DOI: 10.1016/j.critrevonc.2012.02.002

Abstract

There is a general conception among oncologists that CUP patients behave poorly to treatment and carry a dismal survival. In this paper we are trying to elucidate the different groups of CUP patients and to describe in details the diagnostic and therapeutic management of the prognostically favorable patients. Clinicians should be aware that the favorable CUP cases must be treated according to recent guidelines with either specific locoregional and/or systemic therapy and that they commonly enjoy a long survival. Survival data of 219 CUP patients treated at Ioannina University Hospital from 1995 until 2011 are also presented.

Publication types

Review

MeSH terms

Female
Humans
Male
Neoplasms, Unknown Primary / classification
Neoplasms, Unknown Primary / diagnosis*
Neoplasms, Unknown Primary / pathology
Survivors*