NMR assignment of a PDZ domain in complex with a HPV51 E6 derived N-terminally pyroglutamic acid modified peptide

André Mischo; Oliver Ohlenschläger; Ramadurai Ramachandran; Matthias Görlach

doi:10.1007/s12104-012-9374-1

NMR assignment of a PDZ domain in complex with a HPV51 E6 derived N-terminally pyroglutamic acid modified peptide

Biomol NMR Assign. 2013 Apr;7(1):47-9. doi: 10.1007/s12104-012-9374-1. Epub 2012 Mar 6.

Authors

André Mischo¹, Oliver Ohlenschläger, Ramadurai Ramachandran, Matthias Görlach

Affiliation

¹ Leibniz-Institut für Altersforschung/Fritz-Lipmann-Institut, Beutenbergstr. 11, 07745, Jena, Germany.

PMID: 22392342
DOI: 10.1007/s12104-012-9374-1

Abstract

The resonance assignment of an amino-terminal pyroglutamic acid containing peptide derived from the E6 protein of human papillomavirus (HPV) type 51 in complex with PDZ domain 2 of hDlg/SAP-97 is reported. The assignments include (1)H, (13)C and (15)N resonances for the protein and peptide in the complex and all of the peptide's pyroglutamic acid nuclei.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Nuclear Magnetic Resonance, Biomolecular*
Oncogene Proteins, Viral / chemistry*
PDZ Domains*
Papillomaviridae*
Peptide Fragments / chemistry*
Peptide Fragments / metabolism*
Pyrrolidonecarboxylic Acid / chemistry*

Substances

Oncogene Proteins, Viral
Peptide Fragments
Pyrrolidonecarboxylic Acid