Objective: To review the progress and clinical application of cellular therapy for stress urinary incontinence (SUI).
Methods: The literature about cellular therapy of SUI was extensively reviewed.
Results: Because of having no or poor regeneration capacity, the clinical application of chondrocytes and myoblasts were limited. Based on the rapid progress in stem cell biology, an increasing number of animal experiments and clinical trials about cellular therapy of SUI have been reported with encouraging results. All these show that cellular therapy has great potential in clinical application. Stem cells are considered as ideal seeded-cells for treatment of SUI.
Conclusion: Cellular therapy, especially stem cells, provides a novel approach for treatment of SUI, but the mechanism needs further study.