Role of induced negative and positive emotions in sensitivity to itch and pain in women

Br J Dermatol. 2012 Aug;167(2):262-9. doi: 10.1111/j.1365-2133.2012.10933.x. Epub 2012 Jun 11.

Abstract

Background: Itch and pain are common symptoms in skin disease. It has been suggested that negative emotions may play a role in itch and pain. To date, however, the role of emotions has only been studied for pain in experimental studies, not yet for itch.

Objectives: To investigate the effects of negative and positive emotions on the sensitivity to itch and pain.

Methods: Film fragments were used to induce a negative or positive emotional state in healthy women. Itch and pain were induced using the following somatosensory stimuli: electrical stimulation, histamine iontophoresis and the cold pressor test.

Results: Results showed that the scores for itch and pain evoked by histamine and the cold pressor test, respectively, were significantly higher in the negative than in the positive emotion condition, whereas tolerance thresholds to electrical stimulation and the cold pressor test, and stimulus unpleasantness scores did not differ between the two conditions.

Conclusions: These findings for the first time indicate in an experimental design that emotions play a role in sensitivity to somatosensory sensations of both itch and pain.

MeSH terms

  • Analysis of Variance
  • Cold Temperature
  • Electric Stimulation
  • Emotions*
  • Female
  • Histamine / pharmacology
  • Histamine Agonists / pharmacology
  • Humans
  • Iontophoresis
  • Pain / psychology*
  • Pain Measurement
  • Pruritus / psychology*
  • Self Report
  • Young Adult

Substances

  • Histamine Agonists
  • Histamine