Aneurysm formation after drug-eluting balloon treatment of drug-eluting in-stent restenosis: first case report

Catheter Cardiovasc Interv. 2012 Dec 1;80(7):1223-6. doi: 10.1002/ccd.23460. Epub 2012 Mar 14.

Abstract

A 55-year-old male underwent paclitaxel-eluting stent implantation in a bifurcation lesion of his left anterior descending artery (LAD) during an episode of unstable angina in 2008. A late in-stent restenosis developed 15 months after implantation of the drug-eluting stent (DES) and was treated with paclitaxel eluting balloon. Two months later, during angiography for functional assessment of the significance of lesions in the circumflex artery, an aneurysm at the place of drug-eluting balloon (DEB) inflation was observed. The patient was left on double antiplatelet therapy and scheduled for clinical observation after 3 months and control coronary angiography after 6 months for aneurysm progression follow-up.

Publication types

  • Case Reports

MeSH terms

  • Angina, Unstable / diagnostic imaging
  • Angina, Unstable / therapy*
  • Angioplasty, Balloon, Coronary / adverse effects*
  • Angioplasty, Balloon, Coronary / instrumentation*
  • Aspirin / therapeutic use
  • Cardiac Catheters*
  • Cardiovascular Agents / administration & dosage
  • Clopidogrel
  • Coronary Aneurysm / diagnostic imaging
  • Coronary Aneurysm / etiology*
  • Coronary Angiography
  • Coronary Restenosis / diagnostic imaging
  • Coronary Restenosis / etiology
  • Coronary Restenosis / therapy*
  • Drug Delivery Systems / instrumentation*
  • Drug Therapy, Combination
  • Drug-Eluting Stents*
  • Equipment Design
  • Humans
  • Male
  • Middle Aged
  • Paclitaxel / administration & dosage
  • Platelet Aggregation Inhibitors / therapeutic use
  • Ticlopidine / analogs & derivatives
  • Ticlopidine / therapeutic use
  • Time Factors

Substances

  • Cardiovascular Agents
  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Ticlopidine
  • Paclitaxel
  • Aspirin