Two closely related strains associated with pertussis resurgence in Israel

Pediatr Infect Dis J. 2012 Jul;31(7):761-2. doi: 10.1097/INF.0b013e31824f91cb.

Abstract

Eighty-two isolates of Bordetella pertussis analyzed by pulsed-field gel electrophoresis from the epidemic years, 2007 to 2008, revealed 4 strains with 2 closely related isolates accounting for 95% of the circulating strains. The most common Israeli strain has the same pulsed-field gel electrophoresis cluster as the dominant European BpSR11 strain (pulsed-field gel electrophoresis cluster IVβ) identified in the 1999 to 2004 EU Pertstrain II project.

MeSH terms

  • Adolescent
  • Bordetella pertussis / classification*
  • Bordetella pertussis / genetics
  • Bordetella pertussis / isolation & purification*
  • Child
  • Child, Preschool
  • Cluster Analysis
  • Communicable Diseases, Emerging / epidemiology*
  • Communicable Diseases, Emerging / microbiology*
  • DNA, Bacterial / genetics
  • Electrophoresis, Gel, Pulsed-Field
  • Female
  • Genotype
  • Humans
  • Infant
  • Infant, Newborn
  • Israel / epidemiology
  • Male
  • Molecular Typing
  • Polymorphism, Genetic
  • Whooping Cough / epidemiology*
  • Whooping Cough / microbiology*

Substances

  • DNA, Bacterial